gp130: ELISA Kits
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
6 results for "gp130 ELISA Kits" in Products
6 results for "gp130 ELISA Kits" in Products
gp130: ELISA Kits
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
| Sensitivity: |
0.05 ng/mL (Cell Culture Supernates) 0.08 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | ELISA |
| Assay Range: |
0.125 - 8 ng/mL (Cell Culture Supernates) 0.25 - 16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Applications: | ELISA |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
