GRAP2 Products
GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.
45 results for "GRAP2" in Products
45 results for "GRAP2" in Products
GRAP2 Products
GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #475804 |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #1G12 |
Applications: | IHC, WB, ELISA, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |
Applications: | PAGE |
Applications: | WB |
Applications: | AC |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow, CyTOF-ready |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
Applications: | IHC, WB, Flow |