HBQ1: Proteins and Enzymes

The HBQ1 gene codes a hemoglobin subunit theta-1 protein that is 142 amino acids long at a mass of approximately 15 kDA. The HBQ1 gene is found in human fetal erythroid tissue as it is expressed early in embryonic life (before 5 weeks) and is part of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. HBQ1 has interactions with genes AHSP, HBA1, HBA2, HBB, and CYB5R3. Research has linked the HBQ1 gene to thalassemia and hemoglobinopathy.