HGFR/c-MET Products
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151,
6 results for "HGFR/c-MET" in Products
6 results for "HGFR/c-MET" in Products
HGFR/c-MET Products
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names: | Semaxinib |
| Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity: | ≥99% (HPLC) |
Potent and selective MET inhibitor
| Chemical Name: | (2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine |
| Purity: | ≥98% (HPLC) |
Potent c-MET/ALK inhibitor
| Alternate Names: | PF 02341066,PF 2341066 |
| Chemical Name: | 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine |
| Purity: | ≥99% (HPLC) |
Highly selective MET inhibitor
| Chemical Name: | 4-[1-(6-Quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanol mesylate |
| Purity: | ≥98% (HPLC) |
Selective and potent c-MET kinase inhibitor
| Chemical Name: | 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline |
| Purity: | ≥99% (HPLC) |
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names: | SU 11248 |
| Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity: | ≥99% (HPLC) |
