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Histone H2AX: Proteins and Enzymes

Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.

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5 results for "Histone H2AX Proteins and Enzymes" in Products

5 results for "Histone H2AX Proteins and Enzymes" in Products

Histone H2AX: Proteins and Enzymes

Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.

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Applications: WB, ELISA, MA, AP
Catalog #: H00003014-Q01
Applications: WB, ELISA, MA, AP, PAGE
Applications: WB, PAGE
Applications: AC
Applications: AC
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