HM74A/PUMA-G/GPR109A Products
The low affinity and high affinity receptors for nicotinic acid (niacin) are the inhibitory G-protein coupled receptors HM74/GPR109B and HM74A/GPR109A, respectively. Binding of niacin to HM74A mediates an anti-lipolytic effect observed on adipose tissue. HM74A is also expressed on mouse splenocytes, as niacin and other vitamins can enhance the mitogenic response of lymphocytes.
72 results for "HM74A/PUMA-G/GPR109A" in Products
72 results for "HM74A/PUMA-G/GPR109A" in Products
HM74A/PUMA-G/GPR109A Products
The low affinity and high affinity receptors for nicotinic acid (niacin) are the inhibitory G-protein coupled receptors HM74/GPR109B and HM74A/GPR109A, respectively. Binding of niacin to HM74A mediates an anti-lipolytic effect observed on adipose tissue. HM74A is also expressed on mouse splenocytes, as niacin and other vitamins can enhance the mitogenic response of lymphocytes.
| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, KD |
![Immunohistochemistry-Paraffin: HM74A/PUMA-G/GPR109A/NIACR1 Antibody [NBP1-92180]](https://resources.bio-techne.com/images/products/HM74A-PUMA-G-GPR109A-NIACR1-Antibody-Immunohistochemistry-Paraffin-NBP1-92180-img0004.jpg "Immunohistochemistry-Paraffin: HM74A/PUMA-G/GPR109A/NIACR1 Antibody [NBP1-92180]")
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245115 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2 Monoclonal Clone #MM0329-6S24 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Applications: | WB |
![Western Blot: HM74A/PUMA-G/GPR109A/NIACR1 Overexpression Lysate [NBP2-05008]](https://resources.bio-techne.com/images/products/NIACR1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05008-img0001.jpg "Western Blot: HM74A/PUMA-G/GPR109A/NIACR1 Overexpression Lysate [NBP2-05008]")
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #245106 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rat IgG2 Monoclonal Clone #MM0329-6S24 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rat IgG2 Monoclonal Clone #MM0329-6S24 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #245106 |
| Applications: | Flow, CyTOF-ready |
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors
| Alternate Names: | AY 25712 |
| Chemical Name: | 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid |
| Purity: | ≥99% (HPLC) |
Potent and selective GPR109A (HCA2) agonist
| Chemical Name: | (4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2]pyrazole-3-carboxylic acid |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #245106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2B Monoclonal Clone #245106 |
| Applications: | Flow |