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IL-1 beta/IL-1F2: Simple Plex

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

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10 results for "IL-1 beta/IL-1F2 Simple Plex" in Products

10 results for "IL-1 beta/IL-1F2 Simple Plex" in Products

IL-1 beta/IL-1F2: Simple Plex

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

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Simple Plex Human IL-1 beta /IL-1F2 assay kit contains cartridge, sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).

Applications: Ctrl, Simple Plex

Control for use with Human and Non-Human Primate IL-1 beta/IL-1F2 Simple Plex Cartridge Kit

Applications: Simple Plex

Simple Plex Mouse IL-1 beta/IL-1F2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Mouse IL-1 beta/IL-1F2 Simple Plex Cartridge Kit

Applications: Simple Plex

Simple Plex Non-Human Primate IL-1 beta assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex

Simple Plex 32x8 panel containing IL-1b, IL-12 p70, IL-10 2nd Gen, IL-4 2nd Gen, IL-2, IFNg 3rd Gen, TNF-a 2nd Gen, and IL-6 3rd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).

Applications: Simple Plex

Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 2nd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).

Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 3rd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).

Applications: Simple Plex

Simple Plex 32x4 panel containing IL-1b,IL-6 3rd gen,IL-8,TNF-a 2nd gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).

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