Skip to main content

IL-10 Products

IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

Show More

151 results for "IL-10" in Products

Back to Search Results
应用

151 results for "IL-10" in Products

IL-10 Products

IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

Show More

2 plate pack size has been discontinued.

Applications: WB, Neut
Reactivity: Mouse
Applications: WB, Simple Western, Neut
Reactivity: Human
Applications: WB, Simple Western, IHC, Neut
Reactivity: Human
Applications: WB, ICC
Reactivity: Porcine
Applications: WB, ICC, Neut
Reactivity: Mouse, Rat

Analyzed by SEC-MALS

Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Canine
Results Per Page
5 10 25 50
/ 7