IL-10 Products
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
9 results for "IL-10" in Products
9 results for "IL-10" in Products
IL-10 Products
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
Sensitivity: | 5.5 pg/mL |
Applications: | ELISA |
Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
Reactivity: | Porcine |
Details: | Goat IgG Polyclonal |
Applications: | WB, ICC |
Assay Range: | 23.4 - 1,500 pg/mL |
Applications: | ELISA |
Source: | E. coli |
Accession #: | Q29055 |
Applications: | BA |
Reactivity: | Porcine |
Details: | Mouse IgG2b Monoclonal Clone #148801 |
Applications: | Neut |
Reactivity: | Porcine |
Details: | Mouse IgG2b Monoclonal Clone #262715 |
Applications: | ICC |
Reactivity: | Porcine |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Porcine |
Details: | Mouse IgG2a Monoclonal Clone #148806 |
Applications: | WB |