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IL-12/IL-23 p40 Products

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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143 results for "IL-12/IL-23 p40" in Products

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143 results for "IL-12/IL-23 p40" in Products

IL-12/IL-23 p40 Products

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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Applications: BA

(HEK293-Expressed)

Applications: Neut
Reactivity: Human
Applications: WB, Neut
Reactivity: Mouse
Applications: WB
Reactivity: Mouse

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Applications: WB, Neut
Reactivity: Human
Reactivity: Porcine
Applications: WB
Reactivity: Human
Reactivity: Mouse
Applications: WB, ICC, Neut
Reactivity: Feline
Applications: WB
Reactivity: Rat
Reactivity: Porcine
Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody For Research Use Only

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