IL-12/IL-23 p40 Products
IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.
Products:
143 results for "IL-12/IL-23 p40" in Products
143 results for "IL-12/IL-23 p40" in Products
IL-12/IL-23 p40 Products
IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.
Products:
Sensitivity: | 2.7 pg/mL |
Applications: | ELISA |
Assay Range: | 11.7 - 750 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Sensitivity: | 4 pg/mL |
Applications: | ELISA |
Assay Range: | 11.7 - 750 pg/mL (Cell Culture Supernates, Serum) |
Sensitivity: | 15 pg/mL |
Applications: | ELISA |
Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Source: | Sf 21 (baculovirus) |
Accession #: | P29460 |
Applications: | BA |
Sensitivity: | 18.2 pg/mL |
Applications: | ELISA |
Assay Range: | 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
(HEK293-Expressed)
Source: | HEK293 |
Accession #: | P29460.1 |
Applications: | BA |
Assay Range: | 15.6 - 1,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #24901 |
Applications: | Neut |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #C17.8 |
Applications: | WB, Neut |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #116224 |
Source: | Sf 21 (baculovirus) |
Accession #: | P43432.1 |
Applications: | BA |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Assay Range: | 78.1 - 5,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #169516 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #30517 |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #31052 |
Reactivity: | Feline |
Details: | Goat IgG Polyclonal |
Applications: | WB, ICC, Neut |
Reactivity: | Rat |
Details: | Mouse IgG2b Monoclonal Clone #319429 |
Applications: | WB |
Reactivity: | Porcine |
Details: | Mouse IgG2b Monoclonal Clone #116211 |
Recombinant Monoclonal Antibody For Research Use Only
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Hu204 |
Applications: | ELISA |