IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
3 results for "IL-17/IL-17A" in Products
3 results for "IL-17/IL-17A" in Products
IL-17/IL-17A Products
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
| Reactivity: | Human, Primate |
| Details: | Mouse IgG2b Monoclonal Clone #41809 |
| Applications: | IHC, IP, Dual ISH-IHC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #50101 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, CyTOF-ready, ICFlow, Neut |
