IL-17A/F Heterodimer Products
IL-17A/F is a secreted disulfide-linked heterodimer of the cytokines IL-17A and IL-17F. IL-17A/F and the IL-17A and IL-17F homodimers are produced by IL-23-activated Th17 cells. The widely expressed receptors IL-17 RA and IL-17 RC form a heterodimer for the binding of IL-17A and IL-17F, as well as the heterodimeric IL-17A/F.
IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent). It is upregulated in immune cells during inflammatory arthritis and contributes to disease severity.
Products:
11 results for "IL-17A/F Heterodimer" in Products
11 results for "IL-17A/F Heterodimer" in Products
IL-17A/F Heterodimer Products
IL-17A/F is a secreted disulfide-linked heterodimer of the cytokines IL-17A and IL-17F. IL-17A/F and the IL-17A and IL-17F homodimers are produced by IL-23-activated Th17 cells. The widely expressed receptors IL-17 RA and IL-17 RC form a heterodimer for the binding of IL-17A and IL-17F, as well as the heterodimeric IL-17A/F.
IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent). It is upregulated in immune cells during inflammatory arthritis and contributes to disease severity.
Products:
Sensitivity: | 2.8 pg/mL |
Applications: | ELISA |
Assay Range: | 7.81 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Assay Range: | 46.9 - 3,000 pg/mL |
Applications: | ELISA |
Source: | CHO |
Accession #: | Q16552 (IL-17A) & Q96PD4 (IL-17F) |
Applications: | BA |
Assay Range: | 156 - 10,000 pg/mL |
Applications: | ELISA |
Source: | E. coli |
Accession #: | Q62386 (IL-17A) & AAM77568 (IL-17F) |
Applications: | BA |
Source: | CHO |
Applications: | BA |
Source: | CHO |
Accession #: | Q61453 (IL-17A) & Q5BJ95 (IL-17F) |
Applications: | BA |
Applications: | ELISA |
Source: | E. coli |
Accession #: | Q16552 (IL-17A) & Q96PD4 (IL-17F) |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #1019404 |
Applications: | Neut |