IL-23 Products
IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
285 results for "IL-23" in Products
285 results for "IL-23" in Products
IL-23 Products
IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
| Source: | Sf 21 (baculovirus) |
| Accession #: | P29460 (p40) & AAG37232 (p19) |
| Applications: | BA |
| Sensitivity: | 4.17 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma) |
| Sensitivity: | 16.3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 39 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 39.1 - 2,500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #727753 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA, IP |
![Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-77257]](https://resources.bio-techne.com/images/products/IL-23A-IL-23-P19-Antibody-Western-Blot-NBP1-77257-img0012.jpg "Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-77257]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #320234 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #320229 |
| Applications: | WB |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human, Canine |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Feline |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #320244 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA |
![Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-76697]](https://resources.bio-techne.com/images/products/IL-23A-IL-23-P19-Antibody-Western-Blot-NBP1-76697-img0006.jpg "Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-76697]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #eBio473P19 (eBio11P19, eBio25P19) |
| Applications: | WB, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Applications: | AC |
| Applications: | WB |
![Western Blot: IL-23A/IL-23 P19 Overexpression Lysate [NBL1-11943]](https://resources.bio-techne.com/images/products/IL23-P19-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11943-img0002.jpg "Western Blot: IL-23A/IL-23 P19 Overexpression Lysate [NBL1-11943]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1F6 |
| Applications: | WB, ELISA |
