IL-28A/IFN-lambda 2 Products
IL‑28A/Interferon-lambda 2) is a type III interferon that is upregulated in response to viral infection. It acts primarily on epithelial cells through a receptor complex that contains IL-10 R beta and IL-28 R alpha/IFN-lambda R1.
IL-28A promotes the Th1 polarization of dendritic cells in the airway (e.g. production of IL-12 p70 and IFN-gamma) and inhibits Th2 and Th17 mediated inflammation. In the liver, however, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses. In contrast, it is upregulated in invasive bladder cancer where it promotes tumor cell migration.
Products:
25 results for "IL-28A/IFN-lambda 2" in Products
25 results for "IL-28A/IFN-lambda 2" in Products
IL-28A/IFN-lambda 2 Products
IL‑28A/Interferon-lambda 2) is a type III interferon that is upregulated in response to viral infection. It acts primarily on epithelial cells through a receptor complex that contains IL-10 R beta and IL-28 R alpha/IFN-lambda R1.
IL-28A promotes the Th1 polarization of dendritic cells in the airway (e.g. production of IL-12 p70 and IFN-gamma) and inhibits Th2 and Th17 mediated inflammation. In the liver, however, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses. In contrast, it is upregulated in invasive bladder cancer where it promotes tumor cell migration.
Products:
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | NP_001019844 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | Q8IZJ0 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #244716 |
| Applications: | Neut |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #248526 |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #244707 |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #248512 |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884103R |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884136R |
| Applications: | ELISA |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #884113R |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #625616 |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #7B9A4 |
| Applications: | IHC, WB, ELISA, CyTOF-ready |
![Western Blot: IL-28A/IFN-lambda 2 Antibody (7B9A4)BSA Free [NBP2-52494]](https://resources.bio-techne.com/images/products/IL-28A-IFN-lambda-2-Antibody-7B9A4-Western-Blot-NBP2-52494-img0005.jpg "Western Blot: IL-28A/IFN-lambda 2 Antibody (7B9A4)BSA Free [NBP2-52494]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #6H9E6 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: IL-28A/IFN-lambda 2 Antibody (6H9E6)BSA Free [NBP2-52495]](https://resources.bio-techne.com/images/products/IL-28A-IFN-lambda-2-Antibody-6H9E6-Western-Blot-NBP2-52495-img0006.jpg "Western Blot: IL-28A/IFN-lambda 2 Antibody (6H9E6)BSA Free [NBP2-52495]")
| Source: | NS0 |
| Accession #: | NP_742150 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG1 kappa Monoclonal Clone #RN28 |
| Applications: | ELISA |
![ELISA: IL-28A/IFN-lambda 2 Antibody (RN28) - BSA Free [NBP2-00455]](https://resources.bio-techne.com/images/products/IL28-Antibody-RN28-ELISA-NBP2-00455-img0001.jpg "ELISA: IL-28A/IFN-lambda 2 Antibody (RN28) - BSA Free [NBP2-00455]")
| Applications: | WB |
![Western Blot: IL-28A/IFN-lambda 2 Overexpression Lysate [NBP2-05197]](https://resources.bio-techne.com/images/products/IL28A-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05197-img0001.jpg "Western Blot: IL-28A/IFN-lambda 2 Overexpression Lysate [NBP2-05197]")
| Applications: | ELISA |
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| Applications: | Bioactivity, PAGE |
![SDS-PAGE: Recombinant Mouse IL-28A/IFN-lambda 2 Protein [NBP2-35074]](https://resources.bio-techne.com/images/products/Mouse-IL-28A-IFN-lambda-2-Protein-SDS-Page-NBP2-35074-img0001.jpg "SDS-PAGE: Recombinant Mouse IL-28A/IFN-lambda 2 Protein [NBP2-35074]")