IL-3: Proteins and Enzymes
Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes.
IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.
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11 results for "IL-3 Proteins and Enzymes" in Products
11 results for "IL-3 Proteins and Enzymes" in Products
IL-3: Proteins and Enzymes
Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes.
IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.
Products:
Analyzed by SEC-MALS
Source: | E. coli |
Accession #: | AAC08706 |
Applications: | BA |
Analyzed by SEC-MALS
Source: | E. coli |
Accession #: | NP_034686 |
Applications: | BA |
Animal-Free.
Source: | E. coli |
Accession #: | AAC08706.1 |
Applications: | BA |
Intended for preclinical researchers who may transition to GMP IL-3 for their clinical work
Source: | E. coli |
Accession #: | AAC08706.1 |
Applications: | BA |
Source: | E. coli |
Accession #: | P97688 |
Applications: | BA |
Applications: | WB, ELISA |
Applications: | PAGE, Bioactivity |
Applications: | Bioactivity, PAGE |
Applications: | PAGE, Bioactivity |
Applications: | PAGE, Bioactivity |
Applications: | PAGE, Bioactivity |