IL-8/CXCL8 Products
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Products:
229 results for "IL-8/CXCL8" in Products
229 results for "IL-8/CXCL8" in Products
IL-8/CXCL8 Products
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Products:
| Sensitivity: | 7.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Sensitivity: | 0.4 pg/mL |
| Applications: | ELISA |
| Assay Range: | 1 - 64 pg/mL (Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P10145.1 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #HuMax-IL8 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG2 Monoclonal Clone #ABX-IL8 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #HuMax-IL8 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #HuMax-IL8 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG2 Monoclonal Clone #ABX-IL8 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG2 Monoclonal Clone #ABX-IL8 |
| Applications: | ELISA, Flow, Func |