Insulysin/IDE Products
Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, but has been detected as a secreted enzyme and associated with the plasma membrane as well. The enzyme is expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. IDE hydrolyzes a variety of regulatory peptides, including insulin, glucagon, atrial natriuretic factor, and transforming growth factor-alpha in vitro. In addition, IDE has been shown to degrade the amyloid beta (A beta) peptide, which polymerizes into the plaques associated with Alzheimer's disease.
54 results for "Insulysin/IDE" in Products
54 results for "Insulysin/IDE" in Products
Insulysin/IDE Products
Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, but has been detected as a secreted enzyme and associated with the plasma membrane as well. The enzyme is expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. IDE hydrolyzes a variety of regulatory peptides, including insulin, glucagon, atrial natriuretic factor, and transforming growth factor-alpha in vitro. In addition, IDE has been shown to degrade the amyloid beta (A beta) peptide, which polymerizes into the plaques associated with Alzheimer's disease.
| Source: | Sf 21 (baculovirus) |
| Accession #: | P14735 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #GT143 |
| Applications: | IHC, WB |
![Western Blot: Insulysin/IDE Antibody (GT143) [NBP3-13560]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-GT143-Western-Blot-NBP3-13560-img0005.jpg "Western Blot: Insulysin/IDE Antibody (GT143) [NBP3-13560]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #334501 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S04-4E8 |
| Applications: | WB, ICC/IF |
![Western Blot: Insulysin/IDE Antibody (S04-4E8) [NBP3-19987]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-S04-4E8-Western-Blot-NBP3-19987-img0002.jpg "Western Blot: Insulysin/IDE Antibody (S04-4E8) [NBP3-19987]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #GT286 |
| Applications: | IHC, WB |
![Western Blot: Insulysin/IDE Antibody (GT286) [NBP3-13547]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-GT286-Western-Blot-NBP3-13547-img0004.jpg "Western Blot: Insulysin/IDE Antibody (GT286) [NBP3-13547]")
| Source: | Sf 21 (baculovirus) |
| Accession #: | P35559 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Insulysin/IDE Antibody [NB100-68148]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-Western-Blot-NB100-68148-img0009.jpg "Western Blot: Insulysin/IDE Antibody [NB100-68148]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, KO |
![Western Blot: Insulysin/IDE AntibodyBSA Free [NBP3-03392]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-Western-Blot-NBP3-03392-img0002.jpg "Western Blot: Insulysin/IDE AntibodyBSA Free [NBP3-03392]")
| Applications: | ELISA |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Insulysin/IDE Antibody [NB100-61667]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-Western-Blot-NB100-61667-img0003.jpg "Western Blot: Insulysin/IDE Antibody [NB100-61667]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Insulysin/IDE Antibody [NBP2-38994]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-Western-Blot-NBP2-38994-img0003.jpg "Western Blot: Insulysin/IDE Antibody [NBP2-38994]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
![Knockout Validated: Insulysin/IDE Antibody [NBP2-16914]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-Western-Blot-NBP2-16914-img0004.jpg "Knockout Validated: Insulysin/IDE Antibody [NBP2-16914]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #8O8F3 |
| Applications: | WB |
![Western Blot: Insulysin/IDE Antibody (8O8F3) [NBP3-15352]](https://resources.bio-techne.com/images/products/Insulysin-IDE-Antibody-8O8F3-Western-Blot-NBP3-15352-img0001.jpg "Western Blot: Insulysin/IDE Antibody (8O8F3) [NBP3-15352]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C2 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C1 |
| Applications: | IHC, WB, ICC/IF |
| Applications: | ELISA |
| Applications: | ELISA |
