Jagged 1: Proteins and Enzymes
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of the heart, eye, and vertebrae, as well as a characteristic facial appearance.
Products:
8 results for "Jagged 1 Proteins and Enzymes" in Products
8 results for "Jagged 1 Proteins and Enzymes" in Products
Jagged 1: Proteins and Enzymes
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of the heart, eye, and vertebrae, as well as a characteristic facial appearance.
Products:
| Source: | CHO |
| Accession #: | P78504 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q63722.2 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | P78504.3 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q9QXX0.1 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | P78504.3 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P78504 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q63722 |
| Applications: | BA |
| Applications: | AC |