Kv8.2: Proteins and Enzymes

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from bothfunctional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heartrate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cellvolume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamilymembers. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channelsubunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.(provided by RefSeq)