Kynureninase: Lysates
Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3-hydroxyanthranilic acid and alanine. KYNU degrades dietary tryptophan in the liver and is involved in the de novo biosynthesis of NAD+. In immune system cells, such as macrophages and microglia, KYNU catalyzes inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer's, stroke, epilepsy, and Huntington's disease.
1 result for "Kynureninase Lysates" in Products
1 result for "Kynureninase Lysates" in Products
Kynureninase: Lysates
Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3-hydroxyanthranilic acid and alanine. KYNU degrades dietary tryptophan in the liver and is involved in the de novo biosynthesis of NAD+. In immune system cells, such as macrophages and microglia, KYNU catalyzes inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer's, stroke, epilepsy, and Huntington's disease.
| Applications: | WB |
![Western Blot: Kynureninase Overexpression Lysate [NBL1-12416]](https://resources.bio-techne.com/images/products/KYNU-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12416-img0002.jpg "Western Blot: Kynureninase Overexpression Lysate [NBL1-12416]")