LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
108 results for "LIGHT/TNFSF14" in Products
108 results for "LIGHT/TNFSF14" in Products
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
Products:
| Source: | NS0 |
| Accession #: | O43557 |
| Applications: | BA |
| Sensitivity: | 16.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, IHC, Neut |
| Source: | NS0 |
| Accession #: | Q9QYH9 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow, CyTOF-ready |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #261639 |
| Applications: | WB |
| Assay Range: | 250 - 16,000 pg/mL |
| Applications: | ELISA |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
For use with catalog number DLIT00
| Applications: | ELISA, Ctrl |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4E3 |
| Applications: | IHC, WB, ELISA, IP |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
Clone 115520 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #115520 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF, ELISA |
![Western Blot: LIGHT/TNFSF14 Antibody [NBP1-51981]](https://resources.bio-techne.com/images/products/LIGHT-TNFSF14-Antibody-Western-Blot-NBP1-51981-img0004.jpg "Western Blot: LIGHT/TNFSF14 Antibody [NBP1-51981]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MM0456-8C34 |
| Applications: | Flow, CyTOF-ready |
![Western Blot: LIGHT/TNFSF14 Antibody (MM0456-8C34)Azide and BSA Free [NBP2-11964]](https://resources.bio-techne.com/images/products/LIGHT-TNFSF14-Antibody-MM0456-8C34-Western-Blot-NBP2-11964-img0001.jpg "Western Blot: LIGHT/TNFSF14 Antibody (MM0456-8C34)Azide and BSA Free [NBP2-11964]")