LILRB1/CD85j/ILT2: Proteins and Enzymes
LILRB1, also known as CD85j and ILT2, is a transmembrane immunoregulatory protein that is expressed on the surface of B cells and monocytes, as well as subsets of NK cells, memory/effector CD8+ T cells, gamma/delta T cells, and monocyte-derived dendritic cells. LILRB1 binds to MHC-I as well as non-classical MHC-I molecules (e.g. HLA-F, HLA-G, and HC-B27), the MHC-I mimetic UL18 encoded by cytomegalovirus, and Angiopoietin-like 7.
Ligation of LILRB1 inhibits the antigen-induced proliferation and activation of CD8+ T cells, CD4+ T cells, NK cells, and gamma/delta T cells. On dendritic cells, ligation inhibits the production of IL-10, IL-12p70, and TGF-beta and protects from Fas-mediated apoptosis.
Products:
5 results for "LILRB1/CD85j/ILT2 Proteins and Enzymes" in Products
5 results for "LILRB1/CD85j/ILT2 Proteins and Enzymes" in Products
LILRB1/CD85j/ILT2: Proteins and Enzymes
LILRB1, also known as CD85j and ILT2, is a transmembrane immunoregulatory protein that is expressed on the surface of B cells and monocytes, as well as subsets of NK cells, memory/effector CD8+ T cells, gamma/delta T cells, and monocyte-derived dendritic cells. LILRB1 binds to MHC-I as well as non-classical MHC-I molecules (e.g. HLA-F, HLA-G, and HC-B27), the MHC-I mimetic UL18 encoded by cytomegalovirus, and Angiopoietin-like 7.
Ligation of LILRB1 inhibits the antigen-induced proliferation and activation of CD8+ T cells, CD4+ T cells, NK cells, and gamma/delta T cells. On dendritic cells, ligation inhibits the production of IL-10, IL-12p70, and TGF-beta and protects from Fas-mediated apoptosis.
Products:
| Source: | HEK293 |
| Accession #: | Q8NHL6 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q8NHL6 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | Q8NHL6.1 |
| Applications: | BA |
Biotinylated
| Source: | NS0 |
| Accession #: | Q8NHL6.1 |
| Applications: | BA |
Biotinylated
| Source: | HEK293 |
| Accession #: | Q8NHL6.1 |
| Applications: | BA |
