Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
83 results for "Mcl-1" in Products
83 results for "Mcl-1" in Products
Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
![Mcl-1 Antibody (OTI10F6) [mFluor Violet 500 SE]](https://resources.bio-techne.com/images/products/nbp2-72598mfv500_mouse-mcl-1-mab-oti10f6-mfluor-violet-500-se-57202313225682.png "Mcl-1 Antibody (OTI10F6) [mFluor Violet 500 SE] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
![Mcl-1 Antibody (OTI10F6) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp2-72598mfv610_mouse-mcl-1-mab-oti10f6-mfluor-violet-610-se-67202399432.png "Mcl-1 Antibody (OTI10F6) [mFluor Violet 610 SE] [NBP2-72598MFV610] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
![Mcl-1 Antibody (OTI10F6) [Alexa Fluor® 350]](https://resources.bio-techne.com/images/products/nbp2-72598af350_mouse-mcl-1-mab-oti10f6-alexa-fluor-350-29820239233860.jpg "Mcl-1 Antibody (OTI10F6) [Alexa Fluor® 350] [NBP2-72598AF350] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |