Melanocortin-1 R/MC1R: Proteins and Enzymes
Melanocortin-1 R/MC1R, the receptor for melanocyte-stimulating hormone (MSH), is a seven pass transmembrane G protein-coupled receptor that controls melanogenesis. Binding of MSH to MC1R activates the receptor and stimulates eumelanin synthesis. MC1R is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.
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Melanocortin-1 R/MC1R: Proteins and Enzymes
Melanocortin-1 R/MC1R, the receptor for melanocyte-stimulating hormone (MSH), is a seven pass transmembrane G protein-coupled receptor that controls melanogenesis. Binding of MSH to MC1R activates the receptor and stimulates eumelanin synthesis. MC1R is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.
Applications: | WB, ELISA, MA, AP, PAGE |