MKK6 Products
MKK6 and the closely related MKK3 are activated by pro-inflammatory cytokines and environmental stresses. Both MKK3 and MKK6 are dual specificity protein kinases, phosphorylating and activating the p38 MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr. Activation of MKK6 occurs through phosphorylation at Ser207 and Thr211 by several upstream MAPK kinase kinases, including ASK1 and TAK1.
11 results for "MKK6" in Products
11 results for "MKK6" in Products
MKK6 Products
MKK6 and the closely related MKK3 are activated by pro-inflammatory cytokines and environmental stresses. Both MKK3 and MKK6 are dual specificity protein kinases, phosphorylating and activating the p38 MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr. Activation of MKK6 occurs through phosphorylation at Ser207 and Thr211 by several upstream MAPK kinase kinases, including ASK1 and TAK1.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #275922 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MKK6/MEK6 [p Ser207] Antibody [NB100-82050]](https://resources.bio-techne.com/images/products/MKK6-MEK6-[p-Ser207]-Antibody-Western-Blot-NB100-82050-img0003.jpg "Western Blot: MKK6/MEK6 [p Ser207] Antibody [NB100-82050]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: MKK6/MEK6 Antibody [NBP1-87791]](https://resources.bio-techne.com/images/products/MKK6-MEK6-Antibody-Immunohistochemistry-Paraffin-NBP1-87791-img0010.jpg "Immunohistochemistry-Paraffin: MKK6/MEK6 Antibody [NBP1-87791]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2F2 |
| Applications: | WB, ELISA, ICC/IF, Func |
![Western Blot: MKK6/MEK6 Antibody (2F2) [H00005608-M02]](https://resources.bio-techne.com/images/products/MKK6-MEK6-Antibody-2F2-Western-Blot-H00005608-M02-img0009.jpg "Western Blot: MKK6/MEK6 Antibody (2F2) [H00005608-M02]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human MKK6/MEK6 His Protein [NBP3-11963]](https://resources.bio-techne.com/images/products/Recombinant-Human-MKK6-MEK6-His-Protein-SDS-Page-NBP3-11963-img0001.jpg "SDS-PAGE: Recombinant Human MKK6/MEK6 His Protein [NBP3-11963]")
| Applications: | WB |
![Western Blot: MKK6/MEK6 Overexpression Lysate [NBL1-12851]](https://resources.bio-techne.com/images/products/MEK6-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12851-img0002.jpg "Western Blot: MKK6/MEK6 Overexpression Lysate [NBL1-12851]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human MKK6/MEK6 His Protein [NBP2-51949]](https://resources.bio-techne.com/images/products/Recombinant-Human-MKK6-MEK6-His-Protein-SDS-Page-NBP2-51949-img0002.jpg "SDS-PAGE: Recombinant Human MKK6/MEK6 His Protein [NBP2-51949]")
| Applications: | AC |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Purity: | ≥99% (HPLC) |
