MKK6/MEK6 [p Ser207] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-82050

Novus Biologicals, part of Bio-Techne
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NB100-82050
NB100-82050-0.025ml
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all MKK6 Antibodies »

Product Specifications

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human MKK6/MEK6 around the phosphorylation site of serine 207 (V-D-SP-V-A).

Modification

p Ser207

Specificity

Detects endogenous levels of MKK6/MEK6 only when phosphorylated at serine207.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MKK6/MEK6 [p Ser207] Antibody

Western Blot: MKK6/MEK6 [p Ser207] Antibody [NB100-82050]

Western Blot: MKK6/MEK6 [p Ser207] Antibody [NB100-82050]

Western Blot: MKK6/MEK6 [p Ser207] Antibody [NB100-82050] - Analysis of extracts from HL60 cells untreated or treated with PMA using MKK6(Phospho-Ser207) antibody

Immunocytochemistry/Immunofluorescence: MKK6/MEK6 [p Ser207] Antibody [NB100-82050] -

Immunocytochemistry/Immunofluorescence: MKK6/MEK6 [p Ser207] Antibody [NB100-82050] - Staining of methanol-fixed Hela cells showing cytoplasmic staining using NB100-82050

Immunohistochemistry-Paraffin: MKK6/MEK6 [p Ser207] Antibody [NB100-82050] -

Immunohistochemistry-Paraffin: MKK6/MEK6 [p Ser207] Antibody [NB100-82050] - Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue, using NB100-82050 (left) or the same antibody preincubated with blocking peptide (right).

Applications for MKK6/MEK6 [p Ser207] Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-200

Immunohistochemistry

1:100-1:300

Immunohistochemistry-Paraffin

1:50-1:100

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% glycerol, 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MKK6

Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.

Long Name

Mitogen-activated Protein Kinase Kinase 6

Alternate Names

MAP2K6, MEK6, PRKMK6, SAPKK3

Entrez Gene IDs

5608 (Human); 114495 (Rat)

Gene Symbol

MAP2K6

UniProt

P52564

Additional MKK6 Products

Product Documents for MKK6/MEK6 [p Ser207] Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MKK6/MEK6 [p Ser207] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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