Nbs1: Lysates
The Nijmegen Breakage Syndrome 1 (Nbs1) protein is a member of the Mre11/Rad50/Nbs1 (MRN) protein complex that binds to DNA double-strand breaks in cells exposed to DNA damaging agents. In addition, the MRN complex colocalizes with replication forks during DNA replication. The MRN complex plays an important role in routine cell cycle progression and genotoxic stress responses by facilitating DNA repair. In fact, mutation of the nbs1 gene and resultant loss of Nbs1 protein expression in humans results in the chromosomal instability disease, Nijmegen Breakage Syndrome.
1 result for "Nbs1 Lysates" in Products
1 result for "Nbs1 Lysates" in Products
Nbs1: Lysates
The Nijmegen Breakage Syndrome 1 (Nbs1) protein is a member of the Mre11/Rad50/Nbs1 (MRN) protein complex that binds to DNA double-strand breaks in cells exposed to DNA damaging agents. In addition, the MRN complex colocalizes with replication forks during DNA replication. The MRN complex plays an important role in routine cell cycle progression and genotoxic stress responses by facilitating DNA repair. In fact, mutation of the nbs1 gene and resultant loss of Nbs1 protein expression in humans results in the chromosomal instability disease, Nijmegen Breakage Syndrome.
| Applications: | WB |
![Western Blot: Nbs1 Overexpression Lysate [NBL1-13497]](https://resources.bio-techne.com/images/products/NBS1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13497-img0002.jpg "Western Blot: Nbs1 Overexpression Lysate [NBL1-13497]")