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NEDD9/CASL Products

NEDD9 (also HEF1 and CASL) is a 93 kDa (predicted) member of the CAS family of proteins. It is widely expressed, and serves to integrate integrin beta 1 and BCR signaling with cell mitotic pathways. Human NEDD9 is 834 amino acids (aa) in length. It contains one SH3 domain (aa 3-65), a Tyr-rich SH2-binding region (aa 90-350), one Ser-rich four alpha-helix bundle protein interaction site (aa 350-650), and an HLH motif that mediates Cas protein dimerization (aa 710-760). NEDD9 usually runs at 105 or 115 kDa in SDS-PAGE due to phosphorylation. It is also cleaved near Leu361 to generate an active N-terminal 55 kDa fragment. One isoform shows a deletion of aa 155-188, while two others show 20 or 7 aa substitutions for aa 155-834 or 1-153, respectively. Over aa 153-366, human and mouse NEDD9 share 85% aa identity.

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43 results for "NEDD9/CASL" in Products

43 results for "NEDD9/CASL" in Products

NEDD9/CASL Products

NEDD9 (also HEF1 and CASL) is a 93 kDa (predicted) member of the CAS family of proteins. It is widely expressed, and serves to integrate integrin beta 1 and BCR signaling with cell mitotic pathways. Human NEDD9 is 834 amino acids (aa) in length. It contains one SH3 domain (aa 3-65), a Tyr-rich SH2-binding region (aa 90-350), one Ser-rich four alpha-helix bundle protein interaction site (aa 350-650), and an HLH motif that mediates Cas protein dimerization (aa 710-760). NEDD9 usually runs at 105 or 115 kDa in SDS-PAGE due to phosphorylation. It is also cleaved near Leu361 to generate an active N-terminal 55 kDa fragment. One isoform shows a deletion of aa 155-188, while two others show 20 or 7 aa substitutions for aa 155-834 or 1-153, respectively. Over aa 153-366, human and mouse NEDD9 share 85% aa identity.

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Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human
Applications: WB, ELISA, ICC/IF, IP
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Catalog #: H00004739-Q01
Applications: WB, ELISA, MA, AP
Catalog #: H00004739-T01
Applications: WB
Applications: WB, ELISA, MA, AP
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC
Reactivity: Human
Applications: IHC
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: AC
Applications: AC
Applications: AC
Applications: AC
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Mouse, Rat
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