Nuclear Receptor Agonists Products
Nuclear receptors are also known as nuclear hormone receptors. They constitute a large family of transcription factors that bind directly to DNA to regulate the expression of target genes. They also regulate the cellular response to hormones like sex steroids, vitamin D3, adrenal steroids and other metabolic ligands. Nuclear receptors are involved in metabolism, development and reproduction.
7 results for "Nuclear Receptor Agonists" in Products
7 results for "Nuclear Receptor Agonists" in Products
Nuclear Receptor Agonists Products
Nuclear receptors are also known as nuclear hormone receptors. They constitute a large family of transcription factors that bind directly to DNA to regulate the expression of target genes. They also regulate the cellular response to hormones like sex steroids, vitamin D3, adrenal steroids and other metabolic ligands. Nuclear receptors are involved in metabolism, development and reproduction.
High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic
| Alternate Names: | Sobetirome |
| Chemical Name: | 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid |
| Purity: | ≥98% (HPLC) |
T cell-specific RORγ (RORγt) agonist
| Chemical Name: | 2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide |
| Purity: | ≥98% (HPLC) |
High affinity Nur77 agonist
| Chemical Name: | Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate |
| Purity: | ≥98% (HPLC) |
Rev-Erbα/β agonist
| Chemical Name: | Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate |
| Purity: | ≥98% (HPLC) |
Selective Rev-Erbα/β agonist; anxiolytic
| Chemical Name: | [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone |
| Purity: | ≥98% (HPLC) |
Nurr1 activator; inhibits NF-κB-dependent gene expression
| Chemical Name: | 3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole] |
| Purity: | ≥98% (HPLC) |
Selective Rev-Erbα agonist
| Alternate Names: | SR 6452 |
| Chemical Name: | 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate |
| Purity: | ≥98% (HPLC) |
