Other ER Stress/UPR Activators: Small Molecules and Peptides
Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.
4 results for "Other ER Stress/UPR Activators Small Molecules and Peptides" in Products
4 results for "Other ER Stress/UPR Activators Small Molecules and Peptides" in Products
Other ER Stress/UPR Activators: Small Molecules and Peptides
Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.
Integrated stress response (ISR) inhibitor
| Chemical Name: | N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] |
| Purity: | ≥99% (HPLC) |
Selective inhibitor of ATF6α; sensitizes cells to ER stress
| Chemical Name: | N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide |
| Purity: | ≥98% (HPLC) |
SERCA2 allosteric activator
| Chemical Name: | 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide |
| Purity: | ≥98% (HPLC) |
ER proteostasis regulator
| Chemical Name: | N-(2-Hydroxy-5-methylphenyl)benzenepropanamide |
| Purity: | ≥98% (HPLC) |
