P-Selectin/CD62P Products
P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.
Products:
8 results for "P-Selectin/CD62P" in Products
8 results for "P-Selectin/CD62P" in Products
P-Selectin/CD62P Products
P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.
Products:
| Source: | NS0 |
| Accession #: | P16109 |
| Applications: | BA |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Sensitivity: | 0.018 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.31 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Source: | CHO |
| Accession #: | P16109 |
| Applications: | BA |
| Reactivity: | Human, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, AdBlk |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #9E1 |
| Applications: | Flow |
| Reactivity: | Human, Equine |
| Details: | Mouse IgG1 Monoclonal Clone #Psel.KO.2.7 |
| Applications: | IHC, ICC/IF, Flow, IP |
