PAK4 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
74 results for "PAK4" in Products
74 results for "PAK4" in Products
PAK4 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
![Western Blot: PAK4 Antibody (OTI1C7) [NBP2-46316]](https://resources.bio-techne.com/images/products/PAK4-Antibody-1C7-Western-Blot-NBP2-46316-img0013.jpg "Western Blot: PAK4 Antibody (OTI1C7) [NBP2-46316]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PAK4 AntibodyBSA Free [NBP1-77236]](https://resources.bio-techne.com/images/products/PAK4-Antibody-Western-Blot-NBP1-77236-img0001.jpg "Western Blot: PAK4 AntibodyBSA Free [NBP1-77236]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, KD |
![Western Blot: PAK4 Antibody [NBP2-58833]](https://resources.bio-techne.com/images/products/PAK4-Antibody-Western-Blot-NBP2-58833-img0003.jpg "Western Blot: PAK4 Antibody [NBP2-58833]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, KD |
![Western Blot: PAK4 Antibody [NBP2-56634]](https://resources.bio-techne.com/images/products/PAK4-Antibody-Western-Blot-NBP2-56634-img0003.jpg "Western Blot: PAK4 Antibody [NBP2-56634]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, WB |
| Reactivity: | Hamster, Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human PAK4 His Protein [NBC1-18517]](https://resources.bio-techne.com/images/products/PAK4-Protein-SDS-Page-NBC1-18517-img0001.jpg "SDS-PAGE: Recombinant Human PAK4 His Protein [NBC1-18517]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3F10 |
| Applications: | WB, ELISA |
![Western Blot: PAK4 Antibody (3F10) [H00010298-M01]](https://resources.bio-techne.com/images/products/PAK4-Antibody-3F10-Western-Blot-H00010298-M01-img0001.jpg "Western Blot: PAK4 Antibody (3F10) [H00010298-M01]")
| Applications: | AC |
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBP2-09153]](https://resources.bio-techne.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09153-img0001.jpg "Western Blot: PAK4 Overexpression Lysate [NBP2-09153]")
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBL1-14080]](https://resources.bio-techne.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14080-img0002.jpg "Western Blot: PAK4 Overexpression Lysate [NBL1-14080]")
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBL1-14081]](https://resources.bio-techne.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14081-img0002.jpg "Western Blot: PAK4 Overexpression Lysate [NBL1-14081]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
Potent PAK4 inhibitor; orally available
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent PAK inhibitor; brain penetrant and orally bioavailable
| Chemical Name: | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
| Purity: | ≥98% (HPLC) |
