PDGF-BB Products
PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.
11 results for "PDGF-BB" in Products
11 results for "PDGF-BB" in Products
PDGF-BB Products
PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.
| Source: | E. coli |
| Accession #: | P01127.1 |
| Applications: | BA |
Animal-Free
| Source: | E. coli |
| Accession #: | P01127 |
| Applications: | BA |
| Sensitivity: | 15 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
Intended for preclinical researchers who may transition to GMP PDGF-BB for their clinical work
| Source: | E. coli |
| Accession #: | P01127.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P01127.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #4# |
| Applications: | WB |
| Applications: | Bioactivity, PAGE |
![SDS-PAGE: Recombinant Human PDGF-BB Protein [NBP2-35203]](https://resources.bio-techne.com/images/products/Human-PDGF-B-Protein-SDS-Page-NBP2-35203-img0001.jpg "SDS-PAGE: Recombinant Human PDGF-BB Protein [NBP2-35203]")