PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
208 results for "PDGF R beta" in Products
208 results for "PDGF R beta" in Products
PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PDGF R beta [p Tyr857] Antibody [NBP3-13248]](https://resources.bio-techne.com/images/products/PDGF-R-beta-[p-Tyr857]-Antibody-Western-Blot-NBP3-13248-img0001.jpg "Western Blot: PDGF R beta [p Tyr857] Antibody [NBP3-13248]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PDGF R beta [p Tyr1009] Antibody [NBP3-13249]](https://resources.bio-techne.com/images/products/PDGF-R-beta-[p-Tyr1009]-Antibody-Western-Blot-NBP3-13249-img0001.jpg "Western Blot: PDGF R beta [p Tyr1009] Antibody [NBP3-13249]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PDGF R beta [p Tyr771] Antibody [NBP3-13250]](https://resources.bio-techne.com/images/products/PDGF-R-beta-[p-Tyr771]-Antibody-Western-Blot-NBP3-13250-img0001.jpg "Western Blot: PDGF R beta [p Tyr771] Antibody [NBP3-13250]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PDGF R beta [p Tyr771] Antibody [NBP3-13239]](https://resources.bio-techne.com/images/products/PDGF-R-beta-[p-Tyr771]-Antibody-Western-Blot-NBP3-13239-img0001.jpg "Western Blot: PDGF R beta [p Tyr771] Antibody [NBP3-13239]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PDGF R beta [p Tyr740] Antibody [NBP3-13269]](https://resources.bio-techne.com/images/products/PDGF-R-beta-[p-Tyr740]-Antibody-Western-Blot-NBP3-13269-img0001.jpg "Western Blot: PDGF R beta [p Tyr740] Antibody [NBP3-13269]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #IMC-2C5 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | WB, Flow, IP |
| Applications: | AC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Kappa Monoclonal Clone #APB5 |
| Applications: | IHC, Flow, MA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Kappa Monoclonal Clone #APB5 |
| Applications: | IHC, Flow, MA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1E8 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1E8 |
| Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #IMC-2C5 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal Clone #rinucumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #IMC-2C5 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #18A2 |
| Applications: | ICC/IF, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #18A2 |
| Applications: | ICC/IF, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #IMC-2C5 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #IMC-2C5 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #18A2 |
| Applications: | ICC/IF, Flow, CyTOF-ready |