PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
255 results for "PDGF R beta" in Products
255 results for "PDGF R beta" in Products
PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
| Reactivity: | Mouse |
| Details: | Rat IgG2a Kappa Monoclonal Clone #APB5 |
| Applications: | IHC, Flow, MA |
![Flow Cytometry: PDGF R beta Antibody (APB5) - BSA Free [NBP1-43349]](https://resources.bio-techne.com/images/products/PDGF-R-beta-Antibody-APB5-Flow-Cytometry-NBP1-43349-img0004.jpg "Flow Cytometry: PDGF R beta Antibody (APB5) - BSA Free [NBP1-43349]")
| Source: | NS0 |
| Accession #: | P09619 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1E8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PDGF R beta Antibody (OTI1E8) [NBP2-46361]](https://resources.bio-techne.com/images/products/PDGF-R-beta-Antibody-OTI1E8-Western-Blot-NBP2-46361-img0009.jpg "Western Blot: PDGF R beta Antibody (OTI1E8) [NBP2-46361]")
| Applications: | ELISA |
| Source: | HEK293 |
| Accession #: | AAA36427.1 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | P05622 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | Q05030.2 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P05622 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | AAA36427.1 |
| Applications: | BA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 250 - 16,000 pg/mL |
| Applications: | ELISA |
Biotinylated
| Source: | CHO |
| Accession #: | AAA36427.1 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #2G7B7 |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
![Western Blot: PDGF R beta Antibody (2G7B7)BSA Free [NBP2-52529]](https://resources.bio-techne.com/images/products/PDGF-R-beta-Antibody-2G7B7-Western-Blot-NBP2-52529-img0007.jpg "Western Blot: PDGF R beta Antibody (2G7B7)BSA Free [NBP2-52529]")
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #42G12 |
| Applications: | IHC, WB, Func, KD |
![Western Blot: PDGF R beta Antibody (42G12) [NBP1-19191]](https://resources.bio-techne.com/images/products/PDGF-R-beta-Antibody-42G12-Western-Blot-NBP1-19191-img0005.jpg "Western Blot: PDGF R beta Antibody (42G12) [NBP1-19191]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #PR7212 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #18A2 |
| Applications: | ICC/IF, Flow, CyTOF-ready |
![Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]](https://resources.bio-techne.com/images/products/PDGF-R-beta-Antibody-18A2-Flow-Cytometry-NBP1-47232-img0002.jpg "Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]")