PKC beta 1 Products
Protein Kinase C (PKC) beta 1 is a member of the PKC family of serine/threonine protein kinases. It is 671 amino acids (aa) in length with a predicted molecular mass of 77 kDa. Human PKC beta 1 shares 98% aa sequence identity with the mouse and rat orthologs. A second PKC beta splice variant, PKC beta 2, contains an alternate C-terminal sequence. Conventional PKC isoforms, including PKC beta 1, require calcium and phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. PKC beta 1 plays a role in B cell receptor signaling and histone demethylation.
5 results for "PKC beta 1" in Products
5 results for "PKC beta 1" in Products
PKC beta 1 Products
Protein Kinase C (PKC) beta 1 is a member of the PKC family of serine/threonine protein kinases. It is 671 amino acids (aa) in length with a predicted molecular mass of 77 kDa. Human PKC beta 1 shares 98% aa sequence identity with the mouse and rat orthologs. A second PKC beta splice variant, PKC beta 2, contains an alternate C-terminal sequence. Conventional PKC isoforms, including PKC beta 1, require calcium and phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. PKC beta 1 plays a role in B cell receptor signaling and histone demethylation.
Reactivity: | Human, Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, ICC |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR3633 |
Applications: | IHC, WB, ICC/IF, Flow |
Selective inhibitor of PKCβII
Chemical Name: | 5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione |
Purity: | ≥99% (HPLC) |
Protein kinase C inhibitor
Alternate Names: | Gö 6850,Bisindolylmaleimide I |
Chemical Name: | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
Purity: | ≥98% (HPLC) |
Potent protein kinase C inhibitor; selective for α and β isozymes
Chemical Name: | 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile |
Purity: | ≥95% (HPLC) |