PKR Products
PKR is activated in response to the presence of double-stranded RNA (dsRNA), most commonly during viral infection where it mediates the antiviral effects of Interferon, and during gene expression manipulation such as siRNA. One substrate of PKR is the eukaryotic initiation factor eIF2 alpha, and phosphorylation of eIF2 alpha by PKR inhibits protein synthesis. In addition, PKR has been shown to be involved in apoptosis, transcriptional regulation, and other downstream pathways pertaining to cancer and various other diseases.
50 results for "PKR" in Products
50 results for "PKR" in Products
PKR Products
PKR is activated in response to the presence of double-stranded RNA (dsRNA), most commonly during viral infection where it mediates the antiviral effects of Interferon, and during gene expression manipulation such as siRNA. One substrate of PKR is the eukaryotic initiation factor eIF2 alpha, and phosphorylation of eIF2 alpha by PKR inhibits protein synthesis. In addition, PKR has been shown to be involved in apoptosis, transcriptional regulation, and other downstream pathways pertaining to cancer and various other diseases.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #HL71/10 |
| Applications: | WB, Simple Western, IP, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PKR AntibodyBSA Free [NBP1-77266]](https://resources.bio-techne.com/images/products/PKR-Antibody-Western-Blot-NBP1-77266-img0009.jpg "Western Blot: PKR AntibodyBSA Free [NBP1-77266]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PKR Antibody (1D11) [H00005610-M02]](https://resources.bio-techne.com/images/products/PKR-Antibody-1D11-Western-Blot-H00005610-M02-img0012.jpg "Western Blot: PKR Antibody (1D11) [H00005610-M02]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #6H3A10 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: PKR Antibody (6H3A10)BSA Free [NBP2-37242]](https://resources.bio-techne.com/images/products/PKR-Antibody-6H3A10-Western-Blot-NBP2-37242-img0010.jpg "Western Blot: PKR Antibody (6H3A10)BSA Free [NBP2-37242]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SY230 |
| Applications: | IHC, WB, ICC/IF, IP, ChIP |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #S08-2C8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PKR Antibody (S08-2C8) [NBP3-19517]](https://resources.bio-techne.com/images/products/PKR-Antibody-S08-2C8-Western-Blot-NBP3-19517-img0003.jpg "Western Blot: PKR Antibody (S08-2C8) [NBP3-19517]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2125 |
| Applications: | IHC, WB, IP, ChIP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PKR [p Thr446] Antibody [NB100-82156]](https://resources.bio-techne.com/images/products/PKR-[p-Thr446]-Antibody-Western-Blot-NB100-82156-img0002.jpg "Western Blot: PKR [p Thr446] Antibody [NB100-82156]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2F8 |
| Applications: | IHC, WB, ELISA, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S04-3F2 |
| Applications: | WB |
![Western Blot: PKR Antibody (S04-3F2) [NBP3-19538]](https://resources.bio-techne.com/images/products/PKR-Antibody-S04-3F2-Western-Blot-NBP3-19538-img0001.jpg "Western Blot: PKR Antibody (S04-3F2) [NBP3-19538]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human PKR GST (N-Term) Protein [H00005610-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00005610-Q01-1.jpg "SDS-PAGE: Recombinant Human PKR GST (N-Term) Protein [H00005610-Q01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: PKR Antibody [NBP1-84878]](https://resources.bio-techne.com/images/products/PKR-Antibody-Immunohistochemistry-Paraffin-NBP1-84878-img0002.jpg "Immunohistochemistry-Paraffin: PKR Antibody [NBP1-84878]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #5B7B6 |
| Applications: | WB |
![Western Blot: PKR Antibody (5B7B6) [NBP3-15767]](https://resources.bio-techne.com/images/products/PKR-Antibody-5B7B6-Western-Blot-NBP3-15767-img0001.jpg "Western Blot: PKR Antibody (5B7B6) [NBP3-15767]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #JE46-70 |
| Applications: | WB, ICC/IF, Flow |
![PKR [p Thr451] Antibody (JE46-70)](https://resources.bio-techne.com/images/products/nbp3-32789_rabbit-pkr-p-thr451-mab-je46-70-288202412442954.jpg "Western Blot: PKR [p Thr451] Antibody (JE46-70) [NBP3-32789]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PKR [p Thr446] Antibody [NBP3-13141]](https://resources.bio-techne.com/images/products/PKR-[p-Thr446]-Antibody-Western-Blot-NBP3-13141-img0001.jpg "Western Blot: PKR [p Thr446] Antibody [NBP3-13141]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PKR Antibody [NBP2-57020]](https://resources.bio-techne.com/images/products/PKR-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-57020-img0001.jpg "Immunocytochemistry/ Immunofluorescence: PKR Antibody [NBP2-57020]")
| Applications: | WB |
![Western Blot: PKR Overexpression Lysate [NBP2-11096]](https://resources.bio-techne.com/images/products/PKR-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11096-img0001.jpg "Western Blot: PKR Overexpression Lysate [NBP2-11096]")
| Applications: | WB |
![Western Blot: PKR Overexpression Lysate [NBL1-10176]](https://resources.bio-techne.com/images/products/PKR-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10176-img0002.jpg "Western Blot: PKR Overexpression Lysate [NBL1-10176]")
| Applications: | ELISA |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
PKR inhibitor
| Chemical Name: | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
| Purity: | ≥98% |
