RPL11: Proteins and Enzymes

RPL11, also known as 60S ribosomal protein L11, is a 20kDa 178 amino acid protein with a shorter 20kDa 177 isoform produced by alternative splicing. RPL11 is required for rRNA maturation and can be found in the nucleus. Current research is being conducted on RPL11 in relation to aplastic anemia, anemia, pneumonia, retinitis, tuberculosis, malaria and mycobacterium tuberculosis. RPL11 has been linked to the cell cycle arrest, cell proliferation, methylation and translation pathways where it interacts with RPS15A, RPS3, RPS2, RPL26 and MDM2.