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SorCS3: Proteins and Enzymes

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

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2 results for "SorCS3 Proteins and Enzymes" in Products

2 results for "SorCS3 Proteins and Enzymes" in Products

SorCS3: Proteins and Enzymes

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

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Applications: Bind
Applications: Bind
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