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ST2/IL-33R: Simple Plex

ST2, also known as IL-1R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor.

IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated with aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

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5 results for "ST2/IL-33R Simple Plex" in Products

5 results for "ST2/IL-33R Simple Plex" in Products

ST2/IL-33R: Simple Plex

ST2, also known as IL-1R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor.

IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated with aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

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Applications: Simple Plex

Simple Plex Human ST2/IL-33R/IL-1R4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Human ST2/IL-33R/IL-1R4 Simple Plex Cartridge Kit

Applications: Simple Plex

Simple Plex Mouse ST2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Applications: Simple Plex

Control for use with Mouse ST2/IL-33R/IL-1R4 Simple Plex Assay Cartridge Kit

Applications: Simple Plex
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