STIM1: Lysates
STIM-1 (stromal interaction molecule 1), previously called GOK, is a 90 kDa type I transmembrane protein of the endoplasmic reticulum (ER). When STIM-1 senses depletion of calcium in the ER via its EF-hand domain, it interacts with the plasma membrane Ca2+ release-activated Ca2+ (CRAC) channel Orai1, increasing Ca2+ influx. Defects in STIM1 are the cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 2 (IDTICED2).
1 result for "STIM1 Lysates" in Products
1 result for "STIM1 Lysates" in Products
STIM1: Lysates
STIM-1 (stromal interaction molecule 1), previously called GOK, is a 90 kDa type I transmembrane protein of the endoplasmic reticulum (ER). When STIM-1 senses depletion of calcium in the ER via its EF-hand domain, it interacts with the plasma membrane Ca2+ release-activated Ca2+ (CRAC) channel Orai1, increasing Ca2+ influx. Defects in STIM1 are the cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 2 (IDTICED2).
| Applications: | WB |
![Western Blot: STIM1 Overexpression Lysate [NBL1-16538]](https://resources.bio-techne.com/images/products/Stromal-interaction-molecule-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-16538-img0002.jpg "Western Blot: STIM1 Overexpression Lysate [NBL1-16538]")