Substance P Products
Substance P (SP, Neurokinin-1), is member of the Tachykinin peptide family and binds primarily to the Neurokinin 1 Receptor (NK1R, Substance P receptor, Tachykinin receptor 1) and with low affinity to the NK2 and NK3 receptors. Substance P is processed from preproTachykinin a, b, g and d isoforms that also generate other Tachykinins Neuropeptide K, Neurokinin A, Neurokinin B, and Neuropeptide G. Substance P is produced in the central nervous system, primary sensory neurons (C-type fibers), and endocrine cells of the intestinal mucosa. It triggers pain signals in the spinal cord dorsal horn as well as hypotension, tachycardia, release of inflammatory mediators, and direct antimicrobial action.
19 results for "Substance P" in Products
19 results for "Substance P" in Products
Substance P Products
Substance P (SP, Neurokinin-1), is member of the Tachykinin peptide family and binds primarily to the Neurokinin 1 Receptor (NK1R, Substance P receptor, Tachykinin receptor 1) and with low affinity to the NK2 and NK3 receptors. Substance P is processed from preproTachykinin a, b, g and d isoforms that also generate other Tachykinins Neuropeptide K, Neurokinin A, Neurokinin B, and Neuropeptide G. Substance P is produced in the central nervous system, primary sensory neurons (C-type fibers), and endocrine cells of the intestinal mucosa. It triggers pain signals in the spinal cord dorsal horn as well as hypotension, tachycardia, release of inflammatory mediators, and direct antimicrobial action.
Sensitivity: | 43.8 pg/mL |
Applications: | ELISA |
Assay Range: | 39 - 2,500 pg/mL (Cell Culture Supernates) |
Sensory neuropeptide; inflammatory mediator
Purity: | ≥95% (HPLC) |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #SR2325 |
Applications: | IHC |
Reactivity: | Mouse, Multi-Species |
Details: | Rat IgG2A Monoclonal Clone #NC1/34 |
Applications: | IHC |
Potent and selective NK1 agonist
Purity: | ≥95% (HPLC) |
For use with catalog numbers KGE007, SKGE007, PKGE008
Applications: | ELISA, Ctrl |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JE59-73 |
Applications: | IHC |
Reactivity: | Rat |
Details: | Rabbit Polyclonal |
Applications: | IHC, ELISA, ICC/IF |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Applications: | ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #266815 |
Applications: | IHC |