TLR4: Small Molecules and Peptides
TLR4, also known as CD284, is a 100 kDa transmembrane pattern recognition receptor. It associates with MD-2 on monocytes, macrophages, dendritic cells, and B cells where it functions as a receptor for bacterial endotoxin/lipopolysaccharide (LPS). LPS is extracted from circulating CD14-LPS complexes and triggers a TLR4 mediated inflammatory response.
Products:
6 results for "TLR4 Small Molecules and Peptides" in Products
6 results for "TLR4 Small Molecules and Peptides" in Products
TLR4: Small Molecules and Peptides
TLR4, also known as CD284, is a 100 kDa transmembrane pattern recognition receptor. It associates with MD-2 on monocytes, macrophages, dendritic cells, and B cells where it functions as a receptor for bacterial endotoxin/lipopolysaccharide (LPS). LPS is extracted from circulating CD14-LPS complexes and triggers a TLR4 mediated inflammatory response.
Products:
| Applications: | Flow, Func, B/N |
TLR4 signaling inhibitor
| Chemical Name: | (R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate |
| Purity: | ≥98% (HPLC) |
TLR4 inhibitor
| Chemical Name: | 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate |
Immunomodulator; reduces production of pro-inflammatory cytokines
| Chemical Name: | 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid |
| Purity: | ≥98% (HPLC) |
PDE inhibitor (non-selective)
| Alternate Names: | KC-404 |
| Chemical Name: | 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
| Purity: | ≥98% (HPLC) |
