TULA/STS-2: Proteins and Enzymes

UBASH3A, ubiquitin associated and SH3 domain containing, A, interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface (referenced from Swiss Prot).