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Ubiquitin Ligase (E3) Inhibitors: Small Molecules and Peptides

39 results for "Ubiquitin Ligase (E3) Inhibitors Small Molecules and Peptides" in Products

39 results for "Ubiquitin Ligase (E3) Inhibitors Small Molecules and Peptides" in Products

Ubiquitin Ligase (E3) Inhibitors: Small Molecules and Peptides

MDM2 antagonist; inhibits MDM2-p53 interaction

HECT E3 ubiquitin ligase inhibitor

SPOP E3 ubiquitin ligase inhibitor

Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

β-TrCP1 ligase inhibitor

Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination

Cdc20 inhibitor; inhibits Cdc20-substrate interaction

Selective Skp2 inhibitor; suppresses E3 ligase activity

(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4

CHIP/STUB1 E3 ligase inhibitor

Selective GID4 antagonist

Potent and selective CSN5 (COP9 signalosome) inhibitor

MDM2-p53 interaction inhibitor

Selective CUL4 inhibitor

Potent and selective cereblon Degrader (PROTAC®); cell-permeable

High-affinity inhibitor of VHL

Cereblon binder; also TNF-α inhibitor and antiangiogenic

MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Hdm2 inhibitor; activates p53-dependent transcription

RNF114 inhibitor

Molecular glue; pre-mRNA splicing modulator

High affinity MDM2 inhibitor

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

TRAF6-Ubc13 interaction inhibitor

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