VEGF Receptor Inhibitors: Small Molecules and Peptides
15 results for "VEGF Receptor Inhibitors Small Molecules and Peptides" in Products
15 results for "VEGF Receptor Inhibitors Small Molecules and Peptides" in Products
VEGF Receptor Inhibitors: Small Molecules and Peptides
Potent FGFR and VEGFR inhibitor
Chemical Name: | 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
Purity: | ≥95% (HPLC) |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Alternate Names: | Semaxinib |
Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
Purity: | ≥99% (HPLC) |
Potent VEGFR, PDGFR and FGFR inhibitor
Chemical Name: | Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate |
Purity: | ≥98% |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Chemical Name: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
Purity: | ≥98% (HPLC) |
Potent, selective inhibitor of VEGFR-2
Chemical Name: | 5-((7-Benzyloxyquinazolin-4-yl)amino)-4-fluoro-2-methylphenol hydrochloride |
Purity: | ≥99% (HPLC) |
Potent VEGFR inhibitor; also aromatase inhibitor
Alternate Names: | CGP 79787D,PTK787/ZK222584 |
Chemical Name: | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate |
Purity: | ≥99% (HPLC) |
Potent inhibitor of VEGFR, PDGFR and FGFR
Chemical Name: | 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline |
Purity: | ≥98% (HPLC) |
Potent VEGFR inhibitor; also inhibits other RTKs
Alternate Names: | Cabozantinib,BMS 907351 |
Chemical Name: | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
Purity: | ≥98% (HPLC) |
Potent EGFR and VEGFR inhibitor
Chemical Name: | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Purity: | ≥98% (HPLC) |
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
Chemical Name: | N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine |
Purity: | ≥98% (HPLC) |
Potent, selective VEGFR-2 inhibitor
Chemical Name: | N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea |
Purity: | ≥97% (HPLC) |
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
Chemical Name: | N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine trifluoroacetate |
Purity: | ≥98% (HPLC) |
Potent VEGFR, PDGFRβ and KIT inhibitor
Alternate Names: | SU 11248 |
Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
Purity: | ≥99% (HPLC) |
Potent VEGFR-1, -2 and -3 inhibitor
Chemical Name: | N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
Purity: | ≥99% (HPLC) |
Potent multi-kinase and pan-Bcr-Abl inhibitor
Alternate Names: | Ponatinib |
Chemical Name: | 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide |
Purity: | ≥98% (HPLC) |