RNAscope multiomics on COMET spatial biology image

Delivering Spatial Insights to Improve Lives

 

Bio-Techne is a global leader in spatial biology, delivering powerful multiomic solutions to reveal ground-breaking discoveries, accelerate the development of next-generation therapeutics, and deliver life changing diagnostics. Reveal new insights in cell phenotype and function with confidence using gold-standard RNAscope™ technology, proven Bio-Techne antibodies, and the fully automated Lunaphore COMET™ system.

See More With RNAscope™

Many Spatial Questions. One Clear Answer. 

  • Accurately detect RNA expression at single-molecule sensitivity and subcellular resolution.​

  • Visualize and quantify any RNA. Select from mRNAs, ncRNAs, splice variants, reporters, transgenes and more.​

  • Easily detect RNA and protein biomarkers on the same section for a comprehensive view of single-cell phenotype and function.​

  • Characterize any organism or tissue with proven protocols.

 

 

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Featured Spatial Biology Products and Applications

Detection of cytokines, immune and tumor cells using an RNAscope ​RNA-protein multiomic panel of 4 marker proteins, ​CD4 (yellow), CD8 (white), PanCK (pink), FoxP3 (green), and 2 target RNA probes, IFNG (red), GZMB (turquoise) in human colon cancer tissue

Spatial Multiomics

Visualize cell phenotype and function with protease-free, same-slide codetection of protein and RNA.

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Lunaphore COMET™

Unlock the potential of spatial biology with unmatched hyperplex throughput, walk-away automation, and rapid, flexible panel design.

Profiling different cell types within the brain tumor microenvironment. Simultaneous detection of a panel of 3 marker proteins (CD8a, CD68, S100β) and 3 target RNA probes (CLDN5, CXCL10, TNFα) in brain tumor tissue.

Single Cell Validation

Visualize the spatial localization and activation states of novel cell subtypes.

 

Reveal New Spatial Biology Insights in Health and Disease

Representation of a brain

Neuroscience

Spatially interrogate neuronal cell subtypes, central inflammatory responses, and networks of pain and addiction.

Representation of a tumor

Cancer

Uncover mechanisms underlying cancer initiation, progression, and therapeutic resistance.​

Representation of an immune cell

Inflammation

Quantify and characterize immune cell infiltration and activation including cytokine chemokine expression.

 

Accelerate Therapeutics Development​

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Gene Therapy

Visualize AAV vector and ASO/siRNA biodistribution, cellular tropism, and transduction efficiency in spatial context.​

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Cell Therapy

Quantify infiltration and cellular activation of engineered cells in cancer and diseased tissues.

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