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The Fastest Way to Single Cell Isolation

The Pala Cell Sorter and Single Cell Dispenser is a platform that:

  • Boosts efficiency in the lab by isolating and dispensing cells in ≤ 7 minutes
  • Gives you high-quality, viable cells through gentle sorting (<2 psi)
  • Adapts to a wide range of cell densities, from as little as 100 cell/mL
  • Ensures consistency and ease through full automation
  • Fits into your budget and cell culture hood by being affordable, light-weight, and compact
Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Hear From Other Scientists

Dr. Oscar Perez-Leal describes how his team leveraged a Bio-Techne Single Cell Sorter and Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells.

Dr. Oscar Perez-Leal from Temple University describes how his team leveraged a Bio-Techne Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells.

Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell sorting dispensing technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing.

Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell dispenser technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing.

Sort Cells According to Your Requirements

Leverage the powerful combination of microfluidics, flow cytometry, and liquid dispensing in the Pala system to:

  • Get single cells dispensed into 96- or 384-well plates with the Single Cell Sorting Mode
  • Isolate rare cells from large populations with the Enrichment Mode
  • Easily sort tens of thousands of cells with the Bulk Sorting Mode

Microfluidics in a Cartridge: Sterile, disposable, enables single cell sorting

Flow Cytometry: Cell viability ensured, no prior experience with flow cytometry needed

Liquid Dispensing: Cells dispensed into 97- or 384-well plates in minutes

The Bio-Techne Pala Cell Sorter and Single Cell Dispenser employs three technologies for single cell sorting and dispensing: microfluidics, flow cytometry, and liquid cell dispensing.
A. Microfluidics, B. Flow Cytometry, C. Liquid Dispensing

Featured Resources

Graph showing enrichment High-Titer lgG Clones enabled by the Pala Single Cell Sorting and Dispensing system from Bio-Techne.

Enriching High Titer IgG-producing Clones Application Note

Cold capture coupled with the Pala single cell sorting system enables enrichment of high-titer IgG clones.

Graph displaying Single Cell Isolation enabled by the Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Single Cell Isolation with Minimal Sample Input Application Note

Isolate single cells from a population as small as 100 cells.

Pala Cell Sorter/Single Cell Dispensers vs Conventional Cell Sorters

See how Pala compares with fluorescence-activated cell sorting (FACS)

  Namocell Single Cell Dispensers Traditional Cell Dispensers
Pressure Less than 2 psi 20 - 70 psi
Initiation time 2 - 3 min 30 - 45 min
Processing speed 2 - 50,000 cells/second 2,000 - 20,000 cells/second
Fluorescence channels Up to 11 16
Minimum input 100 cells 200,000 cells
Droplet size 1 µL 0.001 - 0.005 µL
Sheath 6.5 mL/hr 1 - 2 L/hr
Sterile sorting Easy Difficult
96-well sorting Standard Optional
System clogging No Yes
Cost $ $$$

Accelerate Your Workflow

Pala Single Cell Sorting and Single Cell Dispensing instrument workflow vs. traditional FACS workflow

*Chakrabarti, Lina, et al. “Simplifying Stable CHO Cell Line Generation with High Probability of Monoclonality by Using Microfluidic Dispensing as an Alternative to Fluorescence Activated Cell Sorting.” Biotechnology Progress, 10 Mar. 2024, https://doi.org/10.1002/btpr.3441. Accessed 11 Apr. 2024.

Applications of the Pala Single Cell Sorting and Dispensing System

Click an icon below to learn more about how the Pala system empower modern research and therapeutics. You will be redirected to the original Namocell webpage.

Bio-Techne Pala Cell Sorter and Single Cell Dispenser

The Pala System

For more comprehensive cellular analysis needing multiple markers, use the dual-laser Pala system

Disposable microfluidic cell cartridge used with the Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Microfluidic Cell Cartridges

For enhanced throughput, cell viability, and contamination-free sorting, use these disposable microfluidic cartridges with the Pala systems

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