Apolipoprotein E/ApoE Antibody (WUE-4) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60531B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-60531AF350

Alexa Fluor 405

NB110-60531AF405

Alexa Fluor 488

NB110-60531AF488

Alexa Fluor 532

NB110-60531AF532

Alexa Fluor 594

NB110-60531AF594

Alexa Fluor 647

NB110-60531AF647

Alexa Fluor 700

NB110-60531AF700

Alexa Fluor 750

NB110-60531AF750

Allophycocyanin

NB110-60531APC

CoraFluor 1

NB110-60531CL1

DyLight 350

NB110-60531UV

DyLight 405

NB110-60531V

DyLight 488

NB110-60531G

DyLight 550

NB110-60531R

DyLight 594

NB110-60531DL594

DyLight 650

NB110-60531C

DyLight 680

NB110-60531FR

DyLight 755

NB110-60531IR

FITC

NB110-60531F

HRP

NB110-60531H

Janelia Fluor 525

NB110-60531JF525

Janelia Fluor 549

NB110-60531JF549

Janelia Fluor 646

NB110-60531JF646

Janelia Fluor 669

NB110-60531JF669

mFluor Violet 450 SE

NB110-60531MFV450

mFluor Violet 500 SE

NB110-60531MFV500

mFluor Violet 610 SE

NB110-60531MFV610

PE

NB110-60531PE

PerCP

NB110-60531PCP

Forumulation

Catalog #

BSA Free

NB110-60531

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat (Negative)

Applications

CyTOF-ready, ELISA, Flow (Intracellular), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # WUE-4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Apolipoprotein E/ApoE Antibodies »

Product Specifications

Immunogen

Purified human ApoE [UniProt# P02649]

Epitope

Residues 140-160 of purified human ApoE (LDLR receptor binding site).

Reactivity Notes

Reacts with human better than mouse. It does not appear to react with rat brain tissue.

Localization

Secreted

Specificity

This antibody detects ApoE2, ApoE3 and ApoE4 (PMID 2466929).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for Apolipoprotein E/ApoE Antibody (WUE-4) [Biotin]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow (Intracellular)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Apolipoprotein E/ApoE

Lipoproteins are responsible for carrying cholesterol and other fats through the bloodstream as little packages and are essential for the normal breakdown of these molecules. In particular, apolipoprotein E is a major component of specific lipoproteins called very low-density lipoproteins (VLDL). A major function of VLDLs is to remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes. Apolipoprotein E is a type of lipoprotein. Apolipoprotein E is associated with several cardiovascular disorders. There are three isoforms (slightly different forms) of the ApoE lipoprotein. These three isoforms are known as ApoE2, E3 and E4. ApoE2 seems to be one of several genetic factors that plays a part in increased risk of heart attacks and strokes and ApoE4 is a risk factor for coronary artery disease. As well, ApoE4 has been been suggested to play a role in type 2 Alzheimer disease.

Alternate Names

APOE

Gene Symbol

APOE

Additional Apolipoprotein E/ApoE Products

Product Documents for Apolipoprotein E/ApoE Antibody (WUE-4) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Apolipoprotein E/ApoE Antibody (WUE-4) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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