B7-H2/ICOSLG Antibody (ICOSL/3260) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79932JF549

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-79798

Alexa Fluor 350

NBP2-79932AF350

Alexa Fluor 405

NBP2-79932AF405

Alexa Fluor 488

NBP2-79932AF488

Alexa Fluor 532

NBP2-79932AF532

Alexa Fluor 594

NBP2-79932AF594

Alexa Fluor 647

NBP2-79932AF647

Alexa Fluor 700

NBP2-79932AF700

Alexa Fluor 750

NBP2-79932AF750

Allophycocyanin

NBP2-79932APC

Biotin

NBP2-79932B

CoraFluor 1

NBP2-79932CL1

DyLight 350

NBP2-79932UV

DyLight 405

NBP2-79932V

DyLight 488

NBP2-79932G

DyLight 550

NBP2-79932R

DyLight 594

NBP2-79932DL594

DyLight 650

NBP2-79932C

DyLight 680

NBP2-79932FR

DyLight 755

NBP2-79932IR

FITC

NBP2-79932F

HRP

NBP2-79932H

Janelia Fluor 525

NBP2-79932JF525

Janelia Fluor 646

NBP2-79932JF646

Janelia Fluor 669

NBP2-79932JF669

PE

NBP2-79932PE

PerCP

NBP2-79932PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-79932

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # ICOSL/3260

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all B7-H2 Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human B7-H2/ICOSLG protein (around aa 23-149) (exact sequence is proprietary) (Uniprot: O75144)

Localization

Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for B7-H2/ICOSLG Antibody (ICOSL/3260) [Janelia Fluor® 549]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: B7-H2

B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Long Name

B7 Homolog 2

Alternate Names

B7H2, B7RP-1, CD275, GL50, ICOSL, ICOSLG

Gene Symbol

ICOSLG

Additional B7-H2 Products

Product Documents for B7-H2/ICOSLG Antibody (ICOSL/3260) [Janelia Fluor® 549]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for B7-H2/ICOSLG Antibody (ICOSL/3260) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews